Islet Transplantation LUMC News Surprise • @1MEMO 20251020

Diabetic (dutch ‘Suikerzieke) … Parool, 6 Jan 1990 • @1MEMO 20251020

Big surprise today , to encounter this nice news article by journalist Rob van Dijk reporting on our pancreatic islet transplantation breakthrough in the Leiden University Hospital (now LUMC) in the Amsterdam based Dutch national newspaper Parool , Saturday 6 January 1990 (1).

I was searching actually for a better copy of a different news article I have archived on my clinical islet transplantation work (Newspaper Volkskrant 10 April 1999) in the Delpher archive of the National Library of the Netherlands , scrolling the search results, and noticed this Parool article – I didn’t know it existed ;)

Journalist Rob van Dijk did not interview me for the Parool, so I assume his source was the interview I gave for publication in Cicero, the biweekly LUMC publication, and the Dutch newspaper ‘Leidsch Dagblad’, and posted a year ago (2).

The articles reports (my translation from dutch*) :

Transplantation

Islet transplantation has been possible for a few years now, but it doesn’t (yet?) work in humans. The technique itself isn’t that complicated: as many islets of Langerhans as possible are extracted from a pancreas, injected into the diabetic patient’s liver or spleen, and thus, start producing insulin. However, that “thus” is still a bit tricky… …
The major problems lie in the fact that the yield of properly functioning islets is too small (at least 30 percent of the islets must be obtained undamaged to achieve sufficient insulin production after a transplant) and that the suspensions are too impure. Nevertheless, progress is being made.
The best news comes from Leiden University Hospital. There, biologist M. van der Burg, MSc has developed a method to isolate a very high and pure yield of islets from a dog’s pancreas. Van der Burg succeeded in isolating 40 percent of the vital islets from a dog’s pancreas. Through special processing, he was able to completely purify these cell clumps of 90 percent of excess and complicating pancreatic tissue. These islets were injected into the spleen of the same dog, where they produced sufficient insulin. This initial experiment has since been repeated in Leiden with several dogs with the same success. However, major challenges remain, not the least of which is the rejection problem. The Leiden experiments used the dog’s own tissue. The big question remains how the human immune system reacts when islets from a donor are injected.

*NL (dutch) quote :

Transplantatie

Sinds een paar jaar is eilandjestransplantatie wel mogelijk, alleen, bij de mens werkt het (nog?) niet. De techniek is op zichzelf niet zo ingewikkeld: men haalt zoveel mogelijk eilandjes van Langerhans uit een pancreas, spuit die bij de suikerzieke in lever of milt in en dan gaan ze dus insuline maken. Met dat ‘dus’ ligt het echter nog moeilijk… …
De grote problemen schuilen hem erin dat de oogst aan goed werkende eilandjes te gering is (men moet ten minste 30 procent van de eilandjes onbeschadigd te pakken krijgen om na een transplantatie voldoende insulineproduktie te verkrijgen) en dat de suspensies te onzuiver zijn. Toch zit er schot in.
Het beste nieuws komt uit het academisch ziekenhuis te Leiden. Daar heeft de bioloog drs. M. van der Burg een methode ontwikkeld om uit een hondepancreas een zeer hoge en zuivere oogst aan eilandjes te isoleren. Van der Burg slaagde erin uit de alvleesklier van een hond 40 procent van de vitale eilandjes te isoleren, door een speciale bewerking kon hij deze celklompjes voor 90 procent absoluut zuiveren van overbodig en complicerend pancreasweefsel. Deze eilandjes werden ingespoten in de milt van dezelfde hond en produceren daar voldoende insuline. Dit eerste experiment is in Leiden intussen met meerdere honden met hetzelfde succes herhaald. Maar er zijn nog grote problemen op te lossen en bepaald niet het geringste daarvan is dat van de afstoting. Bij de Leidse experimenten werd gebruik gemaakt van eigen weefsel van de hond. De grote vraag blijft hoe het immuunsysteem van de mens reageert als er eilandjes van een donor worden ingespoten.

Notes

1) Transplantatie. “Het Parool”. Amsterdam, 06-01-1990. Retrieved in Delpher on 20-10-2025, https://resolver.kb.nl/resolve?urn=ABCDDD:010834140:mpeg21:p017

2) Islet Transplantation Breakthrough in Leiden University Hospital • 20240830 • Michel van der Burg • michelvanderburg•com • URL https://michelvanderburg.com/2024/08/30/islet-transplantation-breakthrough-in-leiden-university-hospital-20240830/

Citation info : Islet Transplantation LUMC News Surprise • Michel van der Burg • Miracles.Media • @1MEMO 20251020 • URL michelvanderburg.com/2025/10/20/

Amersfoort Transport • @1MEMO 20250918

Amersfoort, Holland, Sep 2013.

Notes

B-roll en route the 13th internationales literaturfestival berlin (13.ilb) working on a Miracles•Media reportage of the 7 Sep 2013 presentation by Simon Gronowski and Koenraad Tinel (Belgium) ‘Finally Free after 70 years’.

Citation info : Amersfoort Transport • @1MEMO 20250918 • Michel van der Burg • Miracles•Media • TakeNode 91700ee1-9546-43fb-be6c-570d0f99b5b6

Amersfoort Transport • @1MEMO 20250917

Amersfoort, Holland, Sep 2013.

Notes

B-roll en route the 13th internationales literaturfestival berlin (13.ilb) working on a Miracles•Media reportage of the 7 Sep 2013 presentation by Simon Gronowski and Koenraad Tinel (Belgium) ‘Finally Free after 70 years’.

Citation info : Amersfoort Transport • @1MEMO 20250917 • Michel van der Burg • Miracles•Media • TakeNode 60cbd409-08aa-4edf-b9b6-1a3cf39e9ff6

Westerbork Girl • 20250916

Westerbork Girls – From left to right: Catharina Frank, Hannelore Cahn, Beatrice Lissauer, Ulla Gross, Lotte Heider-Lehmann and Ruth Pagener. (Source : Westerbork Memorial)

The documentary ‘Westerbork Girl’ (2007), directed by Steffie van den Oord, tells the story of Hannelore Cahn (later Eisinger-Cahn), a Jewish woman imprisoned in Camp Westerbork for more than two years during World War II. She performed as a dancer in the camp revue, attracting the attention of many, including camp commander Gemmeker and Jewish camp policeman Hans Eisinger, member of the Jewish Order Service—also known as “the Jewish SS”.

Westerbork Girl (VPRO 2007)

Hannelore had earlier met actor and resistance fighter Rob de Vries, with whom she was close. Rob smuggled her out of Westerbork by disguising himself as a train stoker and taking her to Amsterdam, where she briefly went into hiding. Hans Eisinger manages to track her down and one week after her escape Hannelore voluntarily accompanies him back to the camp…possibly due to loneliness, Rob’s existing relationship, or pressure from the Order Service to prevent others being deported to Auschwitz. Shortly thereafter, Hannelore and Hans get married in Westerbork.

Hannelore survived the war and avoided punishment after her return. The film reconstructs her story through interviews, archival footage, and music, presenting it as one of survival, love, and the difficult choices faced under Nazi persecution.

Hannelore sings and is still intensely sung about by Louis de Wijze, who witnessed her escape and remembered the revue songs from Westerbork: Ich hab es bei Nacht den Sternen erzählt, Ich liebe Dich.

Powerful documentary—this story, with close-ups of this Westerbork Girl, that resonate with me. Beautiful surprise while researching the use of the Westerborkfilm. Review by Michel van der Burg , editor Settela.Com

Citation info : Westerbork Girl • 20250916 | Michel van der Burg | Settela•Com | ISSN 2949-9313 | URL https://settela.com/2025/09/16

500 Jewish Children • SS Negbah to Israel • 20250820

Summary — October 1948 Dutch cinema news on the departure of the first Jewish ship – the SS Negbah – in Amsterdam, bound for Haifa, Israel, with immigrants, including the circa 500 Jewish Children from Eastern Europe after their one year stay in the Children’s Village Ilaniah in Holland, where they were trained for their future task in Palestine.

500 Jewish Children – Series

Episode #1 — In the first episode the arrival of 500 Jewish Children in Holland by steam train from  the Dutch National Cinema newsreel of Sep 22, 1947 was reported. Displaced children from Eastern Europe, many of whom lost their parents in the Nazi camps. Travelling from Romania to their destination in the Netherlands, the Children’s Village “ILANIAH”, where they would stay for one to two years, to be trained for a mission in Palestine. The children were then between six and fourteen years old (Note 1).

Episode #2 — The second episode of this short series on these 500 Jewish Children, documented their stay and education in this Children’s Village Ilaniah in Apeldoorn (Netherlands), from their arrival Sep 1947 untill the closing of Ilaniah , October 6, 1948, the day the children started their journey to Israel (Note 2).

Episode #3 — Here the third , and final, episode , with the Dutch National Cinema Newsreel of October 1948, documenting the departure of the children of Ilaniah on the first Jewish ship – the SS Negbah (Hebrew for southbound) – in Amsterdam for their journey to Haifa, Israel. This was one of the first ships to transport legal immigrants to Israel.

The SS Negbah – at the quay in Amsterdam, Oktober 1948 (frame video 20250820). Miracles•Media • 20250820_2


In October 1948, in the port of Amsterdam, the Netherlands, the ship Negbah is ceremonially handed over to the Israeli Shipping Company of Haifa. The Israeli national anthem is sung, the flag is raised, and the chairman of the Dutch Zionist League, Professor S. Kleerekoper, delivers a speech. A Torah scroll is carried on board on behalf of the board of the Netherlands – Israelite Main Synagogue and received by the captain.


The Ilaniah children embark on the Negbah in Amsterdam, 6 Oktober 1948. Source : Dutch National Archive (Photo by Ben Merk | Anefo) | Miracles•Media • 20250819_9

The SS NEGBAH starts its first voyage October 6, 1948 with about 600 passengers from Amsterdam to Haifa, including over 400 of the mainly Romanian Jewish children,
after their one year stay in the Children’s Village Ilaniah in Holland, where they had been trained for their future task in Palestine.


The Ilaniah children embark on the Negbah (frame video 20250820). Miracles•Media • 20250820_1

Notes

1. 500 Jewish Children • Arrival in Holland • 20250811 | Michel van der Burg | Miracles•Media | Settela•Com | ISSN 2949-9313 | TakeNode 5c6e966b-5b45-47ef-ba01-17650007ae20 | URL https://settela.com/2025/08/11/

2. 500 Jewish Children • Ilaniah • 20250819 | Michel van der Burg | Miracles•Media | Settela•Com | ISSN 2949-9313 | URL https://settela.com/2025/08/19/500-jewish-children-ilaniah-20250819/

3. Captions (translated from dutch transcript)

This ship was built here years ago.

It sailed under various flags.

Now it has been purchased by the Israeli shipping company, and symbolically transferred in Amsterdam.

Professor Kleerekoper outlines the importance of this Jewish ship for immigration in Israel. And ends his speech with the assurance that he

‘wants to wish a safe journey.
Not only the crew, also the passengers, but also the entire Jewish people, a safe journey in its path, through a difficult economy, in a threatened world , and a great struggle for independence of its own culture.

The board of the Netherlands – Israelite Main Synagogue donates a Torah, which will remain on board as long as the Negbah will transport Jewish emigrants.

The ship’s name is also a slogan: ‘Na Negev’ – To the Negev – a desert area in southern Palestine that Israel claims.

More than a million immigrants can settle here , once this area has been made fertile.

The NEGBAH takes about 600 emigrants on its first voyage, including a number of stateless people, and almost 500 mainly Romanian children, who were temporarily housed in Apeldoorn.

May the passengers find a happy home in their new fatherland. Shalom.

4. NL – Transcript (dutch , original)

Dit schip werd hier jaren geleden gebouwd. Het voer onder verschillende vlaggen.

Nu werd het aangekocht door de Israëlische scheepvaartmaatschappij en in Amsterdam symbolisch overgedragen.

Professor Kleerekoper schetst het belang van dit Joodse schip voor de immigratie in Israël. En eindigt zijn rede met de verzekering dat hij :
‘een behouden vaart wil wensen…niet alleen de bemanning, ook de passagiers, maar ook het gehele joodse volk, een behouden vaart in zijn weg de moeilijke economie in een bedreigde wereld en een grote strijd om zelfstandigheid van de eigen cultuur.’

Het bestuur van de Nederlands-Israelitische Hoofd Synagoge schenkt een wetsrol, die zo lang aan boord zal blijven als de Negbah joodse emigranten zal vervoeren.

De naam van het schip is tevens een leuze, ‘Na Negev’ – Naar de Negev – een woestijnstreek in het zuiden van Palestina, waarop Israël aanspraak maakt.

Meer dan 1 miljoen immigranten zal dit gebied kunnen opnemen, wanneer het eenmaal vruchtbaar zal zijn gemaakt.

De Negbah neemt op zijn eerste reis ongeveer 600 landverhuizers mee, onder wie een aantal statenlozen en bijna 500 in hoofdzaak Roemeense kinderen, die voorlopig in Apeldoorn waren ondergebracht.

Mogen de opvarenden in hun nieuwe vaderland een gelukkig tehuis vinden. Shalom.

Tags #Negbah #children #Jewish #ship #Palestine #Aliyah #Holland #Ilaniah #Romania #Amsterdam #zionism #education #emigration #holocaust #news #history #ww2 #Polygoon #NIHS #torah

Credits

Film source: Dutch cinema news Polygoon Hollands Nieuws (Producer | Oct 1948) courtesy of Netherlands Institute for Sound and Vision (Open Images).

Citation info : 500 Jewish Children • SS Negbah to Israel • 20250820 | Michel van der Burg | Miracles•Media | Settela•Com | ISSN 2949-9313 | TakeNode 2b1da26e-a39c-4d9d-960a-c1ef669d1509 | URL https://settela.com/2025/08/20/