Tag: symposium

24th AIDPIT Workshop Igls • @1MEMO 20260125


Short impression of the 24th Workshop of the AIDPIT Study Group (Artificial Insulin Delivery, Pancreas and Islet Transplantation), in Igls (Innsbruck) Austria, 23-25 January 2005.

Video from January 25th featuring :

(i) the Igls Congress park ;

(ii) the morning opening lecture by Mathias Brendel, with chairs Bart Keymeulen (Brussels, Belgium) and Mathias Brendel (Giessen, Germany), and, in the lecture hall : president Annika Tibell (Sweden) and honorary member Reinhard Bretzel (Germany) ;

(iii) a lunch time meeting with José Oberholzer (Chicago, USA) … not familar yet ;) with that new little Sony T1 camera with a periscopic lens inside .. ;

(iv) one of the afternoon discussion groups (Clinical Islet Transplantation) ;

(v) clips from the plenary oral abstract session with chairs Karin Ulrichs (Germany) and Richard Smith (Bristol , UK) and lectures by Norma Sue Kenyon (Miami , USA) and Piero Marchetti (Pisa, Italy) with discussion by Daniel Brandhorst.

Notes

AIDPIT was known first as AIDSPIT, short for : Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation.
The AIDSPIT study group of the European Association for the Study of Diabetes (EASD) was established in the early 1980s.
In 2000 the acronym AIDSPIT was replaced by ‘AIDPIT’, in order to avoid confusion with the AIDS disease.

The annual meetings are generally held in the little town of Igls, close to Innsbruck in Austria — the first years, early in February, and next, late in January. Once, in the 1990s (following a discussion ‘…why always in Igls?’, the meeting was held in Amsterdam.
From 2011, the annual workshops of AIDPIT continued as a joined meeting with the EPITA — the European Pancreas and Islet Transplant Association — part of the European Society for Organ Transplantation (ESOT).
From 2024 — following the 12th EPITA Symposium & 41st AIDPIT Workshop in 2023 — this symposium is referred to as the EPITA Symposium.

The original film (2016) was uploaded to Vimeo (size 640×480), and posted Jan 25, 2016 (20160125) at blogging site 1-memo.com , URL https://1-memo.com/2016/01/25/24th-aidpit-workshop-igls/

A second, remastered, video edition (2022) was produced by upscaling the original video file (converted to size 1920 × 1440) and adding a caption, and uploaded to YouTube Jan 25, 2022.

This second edition is published now – Jan 25th 2026 – as part of the Science series of posts at my site michelvanderburg.com, started in 2022 to make available online a portfolio of the science section of my CV, a project I hope to finish soon… in a few months.

Portfolio – Science : https://michelvanderburg.com/category/science/

#AIDPIT #EPITAsymposium #Igls #Innsbruck #Tyrol #history #ESOT_EPITA ##AIDSPIT #Austria #islet #Langerhans #isolation #transplantation #pancreas #diabetes #insulin #michelvanderburg #symposium #EASD #ESOT #workshop #EPITA #science

Citation info : 24th AIDPIT Workshop Igls • Michel van der Burg • Miracles•Media • @1MEMO 20260125 • TakeNode 3baced38-ee79-4127-932d-0136293529e7 • URL https://michelvanderburg.com/2026/01/25

Isolation of Islets of Langerhans for Transplantation in Type-1 Diabetic Patients


Isolation of Islets of Langerhans for Transplantation in Type-1 Diabetic Patients.
Here a film made of my ‘powerpoint’ presentation Feb 22, 2000 – on behalf of our Surgical Department – at the Opening Symposium of the Interdivisional GMP (‘Good Manufacturing Practice’) facility of the Leiden University Medical Centre – the LUMC in Leiden, Holland.

Background
I first started – with a background in biochemistry and philosophy – some 20 years earlier (from 1981) research at the Department of Surgery of the Leiden University Hospital (AZL) in the field of transplantation of the pancreas organ to cure diabetes.

Succesful Experiment Islet Transplantation
From 1986 my focus shifted to innovative procedures for the isolation out of the pancreas organ, of the ca 1 million islets of Langerhans – the insulin producing cell clumps with a size between ca 0.1 to 1 mm , that is 0.004 to 0,04 inch.
In 1989 we performed the first successful autologous transplantations in Holland (in collaboration with the Minneapolis Islet Lab with Jane Field and David Sutherland) – for the first time world-wide with pure islets using our novel procedure of using the organ preservation UW solution (University of Wisconsin / collaboration with dr Robert Carter , Du Pont, UK) during isolation in a pre-clinical large animal diabetes model – with long term transplant functioning with near-normal blood sugar regulation.

First series of human islet isolations , 1989-1990
Next in 1989-1990 we performed a first series of islet isolations from human donor pancreases using our novel techniques of isolation and purification in UW organ preservation solution – in association with a European Concerted Action for the Treatment of Diabetes – the Brussels headed (Daniel Pipeleers) ‘Multicenter program on the treatment of diabetes by islet cell transplantation’.

Exploring human islet work
Subsequently – after some years of exploring options for animal to human islet transplantation , using pig pancreas islets – so-called xenotransplantation – I was asked in 1997 to explore the requirements for operationalization of clinical islet transplantation in the LUMC. December 1997 our Surgical Department decided to go for it.

Establishing the human islet isolation laboratory in Leiden.
In 1998 after a month working in dr Camillo Ricordi’s Diabetes Research Institute in Miami, I started a large series of human islet isolation procedures in Leiden, and from september 1998 documenting the detailed GMP (‘Good Manufacturing Practice’) standard operating procedures, as well as ‘building’ our clinical islet isolation clean room with help from the Miami team in close cooperation with dr. Amon Wafelman (department of Clinical Pharmacy & Toxicology) managing the building of our brand new Interdivisional GMP-facility LUMC (IGFL) of six clean rooms and two chemical product laboratories – that was opened officially Feb 22, 2000 with the symposium, a film, and a tour in the GMP facility.
One year later the GMP islet facility was fully operational and summer 2001 we got a cautious green light (GMP license) for clinical transplantation of any high quality – approved – islet preparations.
Around the same time islet transplantation suddenly became very promising with ‘The Edmonton protocol’. However with the fast increase of logistic and financial demands, and reorganization between LUMC divisions it took till 2007 to finally start first transplants by an expanded islet team in the LUMC clinical islet center in Leiden.
Worldwide since 2000 several hundred people have received islet transplants that generally do not result in long term insulin independence , but do help sugar regulation in the transplant recipients.

Notes :
Links to some publications, news paper reports etc will follow later.

Updates:

Post updated with more details 20191215

Presentation ‘Isolation of Islets of Langerhans for Transplantation in Type-1 Diabetic Patients’ by Michel van der Burg, Feb 22, 2000 – Opening Symposium of the Interdivisional GMP facility of the Leiden University Medical Centre, Leiden, Netherlands. Film : 20191213 Michel van der Burg | miracles.media